ARCHETYPE Synoptic details - Colorectal cancer (openEHR-EHR-CLUSTER.synoptic_details_colorectal_carcinoma.v0)

Name: Synoptic details - Colorectal cancer
License: http://creativecommons.org/licenses/by-sa/4.0/

ARCHETYPE ID	openEHR-EHR-CLUSTER.synoptic_details_colorectal_carcinoma.v0
Concept	Synoptic details - Colorectal cancer
Description	Synoptic findings about colorectal cancer found on histopathological examination.
Use	To record detailed findings about examination of tissue related to colorectal cancer. Use as a component archetype in the context of a suite of archetypes that make up a histopathology report.
Purpose	To record synoptic findings about colorectal cancer found on histopathological examination.
References	College of American Pathologists. Protocol for the Examination of Specimens from Patients with Primary Carcinomas of the Colon and Rectum (version: Colon Rectum 4.0.0.1)[Internet]. 2017 Jun ;[cited 2018 Mar 01] Available from: http://www.cap.org/ShowProperty?nodePath=/UCMCon/Contribution%20Folders/WebContent/pdf/cp-colon-17protocol-4001.pdf Royal College of Pathologists. Dataset for colorectal cancer (4th edition) [Internet]. 2017 Dec ;[cited 2018 May 06 ] Available from: https://www.rcpath.org/resourceLibrary/g049-dataset-for-histopathological-reporting-of-colorectal-cancer.html Royal College of Pathologists of Australasia. Colorectal Cancer Structured Reporting Protocol (3rd Edition 2016). [Internet]. 2016;[cited 2018 Mar 01] Available from: https://www.rcpa.edu.au/Library/Practising-Pathology/Structured-Pathology-Reporting-of-Cancer/Cancer-Protocols/Gastrointestinal/Protocol-colorectal-cancer World Health Organization Classification of Tumours Pathology and Genetics of Tumours of the Digestive System, 2010, 4th edition © International Agency for Research on Cancer (IARC). Oslo universitetssykehus. Elektronisk mal for patologirapportering av hovedfunn ved kolorektalresektater med primært karsinom. Malversjon 2.0, dokumentversjon 1.0. 21.07.2017.
Copyright	© openEHR Foundation, Nasjonal IKT HF
Authors	Forfatternavn: Silje Ljosland Bakke Organisasjon: Nasjonal IKT HF, Norway E-post: silje.ljosland.bakke@nasjonalikt.no Opprinnelig skrevet dato: 2018-04-19
Other Details Language	Forfatternavn: Silje Ljosland Bakke Organisasjon: Nasjonal IKT HF, Norway E-post: silje.ljosland.bakke@nasjonalikt.no Opprinnelig skrevet dato: 2018-04-19
OtherDetails Language Independent	{licence=This work is licensed under the Creative Commons Attribution-ShareAlike 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-sa/4.0/., custodian_organisation=Nasjonal IKT, references=College of American Pathologists. Protocol for the Examination of Specimens from Patients with Primary Carcinomas of the Colon and Rectum (version: Colon Rectum 4.0.0.1)[Internet]. 2017 Jun ;[cited 2018 Mar 01] Available from: http://www.cap.org/ShowProperty?nodePath=/UCMCon/Contribution%20Folders/WebContent/pdf/cp-colon-17protocol-4001.pdf Royal College of Pathologists. Dataset for colorectal cancer (4th edition) [Internet]. 2017 Dec ;[cited 2018 May 06 ] Available from: https://www.rcpath.org/resourceLibrary/g049-dataset-for-histopathological-reporting-of-colorectal-cancer.html Royal College of Pathologists of Australasia. Colorectal Cancer Structured Reporting Protocol (3rd Edition 2016). [Internet]. 2016;[cited 2018 Mar 01] Available from: https://www.rcpa.edu.au/Library/Practising-Pathology/Structured-Pathology-Reporting-of-Cancer/Cancer-Protocols/Gastrointestinal/Protocol-colorectal-cancer World Health Organization Classification of Tumours Pathology and Genetics of Tumours of the Digestive System, 2010, 4th edition © International Agency for Research on Cancer (IARC). Oslo universitetssykehus. Elektronisk mal for patologirapportering av hovedfunn ved kolorektalresektater med primært karsinom. Malversjon 2.0, dokumentversjon 1.0. 21.07.2017. , original_namespace=no.nasjonalikt, original_publisher=Nasjonal IKT, custodian_namespace=no.nasjonalikt, MD5-CAM-1.0.1=5BA2D58ADA02C3132A4AD522AB5A8C63, build_uid=5325ef39-36df-42c6-833f-c45609b994a5, revision=0.0.1-alpha}
Keywords	histopathology, cancer, laboratory, lab, malignancy, pathology, colonic, rectal, anal, GI, gastrointestinal, bowel, microscopic, macroscopic
Lifecycle	in_development
UID	48a2846c-507b-4c9d-8ea0-cf17ee8686e8
Language used	en
Citeable Identifier	1078.36.2048
Revision Number	0.0.1-alpha
All	Archetype [runtimeNameConstraintForConceptName=null, archetypeConceptBinding=null, archetypeConceptDescription=Synoptic findings about colorectal cancer found on histopathological examination., archetypeConceptComment=null, otherContributors=Vebjørn Arntzen, Oslo universitetssykehus HF, Norway (Nasjonal IKT redaktør) Koray Atalag, University of Auckland, New Zealand Silje Ljosland Bakke, Nasjonal IKT HF, Norway (Nasjonal IKT redaktør) Matt Cordell, NEHTA, Australia Hans Kristian Haugland, Helse Bergen, Norway (Nasjonal IKT redaktør) Sabine Leh, Helse Bergen, Norway (Nasjonal IKT redaktør) David McKillop, NEHTA, Australia Ian McNicoll, FreshEHR, United Kingdom Cathy Richardson, NEHTA, Australia David Rowed, Ocean Informatics, Australia Sonja Steigen, Universitetssykehuset Nord-Norge, Norway (Nasjonal IKT redaktør) John Tore Valand, Haukeland Universitetssjukehus, Norway (Nasjonal IKT redaktør), originalLanguage=en, translators=, subjectOfData=ubegrenset, archetypeTranslationTree=null, topLevelToAshis={items=[ResourceSimplifiedHierarchyItem [path=/items[at0330], code=at0330, itemType=ELEMENT, level=1, text=Neoadjuvant therapy given, description=Has neoadjuvant therapy been given?, comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0331::Yes [Neoadjuvant therapy has been given.] at0332::No [Neoadjuvant therapy has not been given.] at0333::Not known [It is not known if neoadjuvant therapy has been given.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0006], code=at0006, itemType=SLOT, level=1, text=Resection margin, description=Details about a specified resection margin, including the distance from the tumour to the margin., comment=null, uncommonOntologyItems=null, occurencesFormal=0.., occurencesText=Valgfritt, gjentagende, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Inkluder:* openEHR-EHR-CLUSTER.tumour_resection_margins.v0, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004], code=at0004, itemType=CLUSTER, level=1, text=Macroscopic findings, description=Macroscopic anatomical pathology findings related to colorectal cancer., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0005], code=at0005, itemType=SLOT, level=2, text=Tumour dimensions, description=Details of maximum dimensions of the tumour., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Inkluder: openEHR-EHR-CLUSTER.physical_properties.v0 og spesialiseringer, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0007], code=at0007, itemType=ELEMENT, level=2, text=Maximum extramuscular extension, description=The maximum extramuscular extension of the tumour., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=C_DV_QUANTITY, bindings=null, values=Egenskap: Length Enheter: >=0.0 mm, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0008], code=at0008, itemType=ELEMENT, level=2, text=Anastomotic doughnuts submitted, description=Have anastomotic doughnuts been submitted for analysis?, comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_BOOLEAN, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0009], code=at0009, itemType=CLUSTER, level=2, text=Tumour perforation, description=Findings related to tumour perforation., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0009]/items[at0010], code=at0010, itemType=ELEMENT, level=3, text=Tumour perforation, description=Finding of tumour perforation. Tumor perforation is a macroscopically visible defect through the tumor, so that the bowel lumen is in communication with the external surface of the resection specimen., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0018::Present [Tumour perforation is present.] at0019::Absent [Tumour perforation is absent.] at0420::Equivocal [It is uncertain whether a tumour perforation is present.] at0017::Indeterminate [Presence of tumour perforation has not been determined.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0009]/items[at0011], code=at0011, itemType=ELEMENT, level=3, text=Perforation location, description=The location of a perforation, if present., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0020::Retro/infra peritoneal [The perforation is retro/infra peritoneal.] at0021::Serosal [The perforation is serosal.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0009]/items[at0012], code=at0012, itemType=ELEMENT, level=3, text=Comment, description=Narrative comment on the perforation., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0013], code=at0013, itemType=CLUSTER, level=2, text=For rectal tumours, description=Findings related solely to rectal tumours., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0013]/items[at0014], code=at0014, itemType=ELEMENT, level=3, text=Relationship to anterior peritoneal reflection, description=The relationship of rectal tumour to the lowest level of the anterior peritoneal reflection., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0022::Entirely above [The tumour is entirely above the level of the peritoneal reflection anteriorly.] at0023::Astride [The tumour is astride (or at) the level of the peritoneal reflection anteriorly.] at0024::Entirely below [The tumour is entirely below the level of the peritoneal reflection anteriorly.] at0372::Indeterminate [Relationship to anterior peritoneal reflection has not been determined.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0013]/items[at0015], code=at0015, itemType=ELEMENT, level=3, text=Intactness of the mesorectum, description=An assessment of the intactness of the mesorectum. The specimen is scored according to the worst area., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0027::Complete [A good bulk of mesorectum with a smooth surface. No coning near the tumor. No defects more than 5 mm deep.] at0026::Nearly complete [Moderate bulk of mesorectum. Irregular surface with defects greater than 5 mm, but not extending to the muscularis propria. Moderate degree of coning may be seen.] at0025::Incomplete [Little bulk of mesorectum, very irregular with defects down to the muscularis propria.] at0028::Indeterminate [Intactness of the mesorectum has not been determined.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0373], code=at0373, itemType=ELEMENT, level=2, text=Comment, description=A text comment on the macroscopic findings., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001], code=at0001, itemType=CLUSTER, level=1, text=Microscopic findings, description=Microscopic anatomical pathology findings related to colorectal cancer., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0033], code=at0033, itemType=ELEMENT, level=2, text=Histological tumour type, description=Histologic classification of the tumour., comment=Use of a terminology is preferred. Commonly the WHO classification is used., uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Mulige datatyper: Kodet tekst at0034::Adenocarcinoma [Usual type of colorectal carcinoma.] [ICD-O-3.1::81403] [SNOMED-CT::35917007 \| Adenocarcinoma] at0410::Adenocarcinoma, cribriform comedo-type [Carcinoma with extensive large cribriform glands with central necrosis.] [ICD-O-3.1::82013] [SNOMED-CT::733838009 \| Cribriform comedo-type adenocarcinoma] at0039::Medullary carcinoma [Variant with a solid architecture and prominent tumor infiltrating lymphocytes.] [ICD-O-3.1::85103] [SNOMED-CT::32913002 \| Medullary carcinoma] at0411::Adenocarcinoma, micropapillary type [Variant with small clusters of tumor cells within stromal spaces.] [ICD-O-3.1::82653] [SNOMED-CT::733878002 \| Micropapillary adenocarcinoma] at0035::Mucinous adenocarcinoma [Variant of adenocarcinoma with more than 50% extracellular mucin.] [ICD-O-3.1::84803] [SNOMED-CT::72495009 \| Mucinous adenocarcinoma] at0412::Adenocarcinoma, serrated type [Variant with glandular serration similar to a sessile serrated polyp.] [ICD-O-3.1::82133] [SNOMED-CT::450948005 \| Serrated adenocarcinoma] at0036::Signet ring cell carcinoma [Variant of adenocarcinoma with more than 50% signet ring cells.] [ICD-O-3.1::84903] [SNOMED-CT::87737001 \| Signet ring cell carcinoma] at0038::Adenosquamous carcinoma [A neoplasm comprising both adenocarcinoma and squamous cell carcinoma.] [ICD-O-3.1::85603] [SNOMED-CT::59367005 \| Adenosquamous carcinoma] at0413::Spindle cell carcinoma [A biphasic carcinoma with a spindle- cell sarcomatoid component in which the tumour cells are at least focally immunoreactive for keratins.] [ICD-O-3.1::80323] [SNOMED-CT::65692009 \| Spindle cell carcinoma] at0037::Squamous cell carcinoma [Primary squamous carcinoma excluding upwardly spreading anal tumours.] [ICD-O-3.1::80703] [SNOMED-CT::28899001 \| Squamous cell carcinoma] at0041::Undifferentiated carcinoma [Carcinoma without gland formation, mucin, squamous or neuroendocrine differentiation.] [ICD-O-3.1::80203] [SNOMED-CT::38549000 \| Carcinoma, undifferentiated] at0040::Neuroendocrine tumour G1 [A tumour with neuroendocrine features and a mitotic sount <2 per 10 HPF and/or < 3% Ki67 index.] [ICD-O-3.1::82403] [SNOMED-CT::127572005 \| Neuroendocrine tumour grade 1] at0414::Neuroendocrine tumour G2 [A tumour with neuroendocrine features and a mitotic sount 2-20 per 10 HPF and/or 3-20% Ki67 index.] [ICD-O-3.1::82493] [SNOMED-CT::127573000 \| Neuroendocrine tumour grade 2] at0418::Neuroendocrine carcinoma [A carcinoma with neurendocrine features and a mitotic count >20 per 10 HPF and/or >20% Ki67 index.] [ICD-O-3.1::82463] [SNOMED-CT::55937004 \| Neuroendocrine tumour] at0415::Neuroendocrine carcinoma, large cell [A carcinoma with neurendocrine features composed of intermediate to large cells with a mitotic count >20 per 10 HPF and/or >20% Ki67 index.] [ICD-O-3.1::80133] [SNOMED-CT::128628002 \| Large cell neuroendocrine carcinoma] at0416::Neuroendocrine carcinoma, small cell [A carcinoma with neurendocrine features composed of small cells with a mitotic count >20 per 10 HPF and/or >20% Ki67 index.] [ICD-O-3.1::80413] [SNOMED-CT::719105002 \| Small cell neuroendocrine carcinoma] at0417::Mixed adenoneuroendocrine carcinoma [A carcinoma with morphologicalle recognizable phenotype composed of both epithelial and neuroendocrine elements where at least 30% of either component is identified.] [ICD-O-3.1::82443] [SNOMED-CT::51465000 \| Mixed adenoneuroendocrine carcinoma] Fri eller kodet tekst , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0002], code=at0002, itemType=SLOT, level=2, text=pTNM classification, description=pTNM pathological classification., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Inkluder: openEHR-EHR-CLUSTER.tnm_stage_pathological.v0, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0323], code=at0323, itemType=ELEMENT, level=2, text=Distance of invasion, description=Maximal distance of tumour invasion beyond the muscularis propria., comment=Only applicable for tumors invading beyond the muscularis propria (T3) and not yet having invaded the peritoneum or adjacent structures., uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=C_DV_QUANTITY, bindings=null, values=Egenskap: Length Enheter: >=0.0 mm, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0389], code=at0389, itemType=CLUSTER, level=2, text=Response to neoadjuvant therapy, description=Assessment of response to neoadjuvant therapy., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0389]/items[at0390], code=at0390, itemType=ELEMENT, level=3, text=Description, description=Text description of regression changes after neoadjuvant therapy., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0389]/items[at0003], code=at0003, itemType=SLOT, level=3, text=Details, description=Details of response to neoadjuvant therapy., comment=For example different grading systems, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Inkluder: Alle ikke eksplisitt ekskluderte arketyper, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0269], code=at0269, itemType=CLUSTER, level=2, text=Histological grading, description=Histological tumour grade., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0269]/items[at0391], code=at0391, itemType=SLOT, level=3, text=Grade, description=Histological grading system for colorectal carcinoma., comment=Only adenocarcinomas (not otherwise specified) are graded with a grading system. Squamous cell carcinomas are graded with 3 grades. Tumours after neoadjuvant therapy are not graded. , uncommonOntologyItems=null, occurencesFormal=0.., occurencesText=Valgfritt, gjentagende, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=Not_Set, bindings=null, values=Inkluder:* Alle ikke eksplisitt ekskluderte arketyper, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0269]/items[at0271], code=at0271, itemType=ELEMENT, level=3, text=Comment, description=A text comment on histological grading., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0030], code=at0030, itemType=CLUSTER, level=2, text=Lymph node findings, description=Findings related to the involvement of tumour in lymph nodes., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0030]/items[at0087], code=at0087, itemType=SLOT, level=3, text=Lymph node detail, description=Findings related to the involvement of tumour in lymph nodes., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Inkluder: openEHR-EHR-CLUSTER.lymph_node_metastases.v1, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0030]/items[at0365], code=at0365, itemType=ELEMENT, level=3, text=Status of apical lymph node, description=Status of the highest lymph node closest to the main vascular tie(s)., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0376::Metastasis present [A metastasis in the highest lymph node is detected.] at0377::Metastasis absent [A metastasis in the highest lymph node is not detected.] at0378::Equivocal [It is uncertain whether a metastasis is present or not.] at0379::Indeterminate [The status of the highest lymph node could not be assessed, e.g. because the resection did not contain an apical lymph node.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0030]/items[at0348], code=at0348, itemType=ELEMENT, level=3, text=Comment, description=An additional text comment on lymph node findings., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0403], code=at0403, itemType=CLUSTER, level=2, text=Tumour deposits, description=Details about tumour deposits., comment=Tumour deposits (satellites) are discrete macroscopic or microscopic nodules of cancer in the pericolorectal adipose tissue’s lymph drainage area of a primary carcinoma that are discontinuous from the primary and without histological evidence of residual lymph node or identifiable vascular or neural structures. , uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0403]/items[at0404], code=at0404, itemType=ELEMENT, level=3, text=Assessment of tumour deposits, description=Simple assessment of tumour deposits., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0405::Present [Tumour deposits are detected.] at0406::Absent [Tumour deposits are not detected.] at0407::Equivocal [Det er uncertain whether tumour deposits are present or absent.] at0408::Indeterminate [Presence or absence of tumour deposits has not been assessed.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0403]/items[at0281], code=at0281, itemType=ELEMENT, level=3, text=Number of tumour deposits, description=Number of tumour deposits. Only relevant if lymph node metastasis is absent., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0380::Not applicable [If positive lymph nodes are present, the status of tumour deposits is irrelevant and thus not applicable.] at0388::0 [Tumor deposits are absent.] at0381::1 [One tumor deposit is present.] at0382::2 [Two tumor deposits are present.] at0383::3 [Three tumor deposits are present.] at0384::4 [Four tumor deposits are present.] at0385::5 [Five tumor deposits are present.] at0386::>5 [More than five tumor deposits are present.] at0387::Equivocal [It is uncertain whether tumor deposits are present.] at0284::Indeterminate [Presence of tumour deposits has not been determined.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0403]/items[at0409], code=at0409, itemType=ELEMENT, level=3, text=Comment, description=Comment on tumour deposits., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0278], code=at0278, itemType=CLUSTER, level=2, text=Local tissue invasion, description=Findings related to local tissue invasion by tumour., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0278]/items[at0374], code=at0374, itemType=SLOT, level=3, text=Large vessel (venous) invasion, description=Details of venous tumour invasion., comment=null, uncommonOntologyItems=null, occurencesFormal=0.., occurencesText=Valgfritt, gjentagende, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Inkluder:* openEHR-EHR-CLUSTER.tumour_invasion.v1, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0278]/items[at0277], code=at0277, itemType=SLOT, level=3, text=Small vessel invasion, description=Details of tumour invasion in thin-walled structures (lymphatics, capillaries, venules)., comment=null, uncommonOntologyItems=null, occurencesFormal=0.., occurencesText=Valgfritt, gjentagende, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Inkluder:* openEHR-EHR-CLUSTER.tumour_invasion.v1, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0278]/items[at0286], code=at0286, itemType=SLOT, level=3, text=Perineural invasion, description=Details of perineural invasion by tumour., comment=null, uncommonOntologyItems=null, occurencesFormal=0.., occurencesText=Valgfritt, gjentagende, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Inkluder:* openEHR-EHR-CLUSTER.tumour_invasion.v1, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0263], code=at0263, itemType=CLUSTER, level=2, text=Distant metastasis, description=Findings related to distant metastasis., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0263]/items[at0264], code=at0264, itemType=ELEMENT, level=3, text=Distant metastasis, description=Findings of histologically confirmed distant metastasis., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0362::Present [Evidence of distant metastasis.] at0363::Absent [No evidence of distant metastasis.] at0364::Indeterminate [Evidence of metastasis has not been determined.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0263]/items[at0287], code=at0287, itemType=SLOT, level=3, text=Sites, description=Details of sites of histologically confirmed distant metastases., comment=null, uncommonOntologyItems=null, occurencesFormal=0.., occurencesText=Valgfritt, gjentagende, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Inkluder:* openEHR-EHR-CLUSTER.anatomical_location.v1, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0263]/items[at0265], code=at0265, itemType=ELEMENT, level=3, text=Description, description=A text description of distant metastases., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0366], code=at0366, itemType=CLUSTER, level=2, text=Polyps, description=Findings of polyps., comment=null, uncommonOntologyItems=null, occurencesFormal=0.., occurencesText=Valgfritt, gjentagende, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0366]/items[at0359], code=at0359, itemType=ELEMENT, level=3, text=Type of polyp, description=Type of polyp. Coding of the specific polyp with a terminology is preferred, where possible., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0366]/items[at0338], code=at0338, itemType=ELEMENT, level=3, text=Number of polyps, description=Number of polyps specified above., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_COUNT, bindings=null, values=min: >=0 , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0366]/items[at0367], code=at0367, itemType=ELEMENT, level=3, text=Polyposis syndrome, description=Evidence of polyposis syndrome., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0368::Present [There is evidence of polyposis syndrome.] at0369::Absent [There is no evidence of polyposis syndrome.] at0419::Equivocal [It is uncertain whether a polyposis syndrome is present.] at0370::Indeterminate [Evidence of polyposis syndrome has not been determined.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0366]/items[at0371], code=at0371, itemType=ELEMENT, level=3, text=Comment, description=Comment concerning polyps., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0179], code=at0179, itemType=CLUSTER, level=2, text=Additional findings, description=Additional histopathological findings., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0179]/items[at0250], code=at0250, itemType=ELEMENT, level=3, text=Additional finding, description=A single additional histopathological finding., comment=null, uncommonOntologyItems=null, occurencesFormal=0.., occurencesText=Valgfritt, gjentagende, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Mulige datatyper: Kodet tekst at0293::Synchronous carcinoma [Synchronous carcinoma is present.] at0294::Ulcerative colitis [Ulcerative colitis is present.] at0295::Ulcerative colitis with dysplasia [Ulcerative colitis with dysplasia is present.] at0296::Crohn's disease [Crohn's disease is present.] at0297::Crohn's disease with dysplasia [Crohn's disease with dysplasia is present.] at0340::Diverticulosis [Diverticulosis is present.] Fri eller kodet tekst , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0179]/items[at0220], code=at0220, itemType=ELEMENT, level=3, text=Description, description=A text description of additional findings., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0309], code=at0309, itemType=ELEMENT, level=2, text=Comment, description=A text comment on the microscopic findings., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null]], content=[], state=[], other_participations=[], credentials=[], ism_transition=[], contacts=[], description=[], capabilities=[], identities=[], data=[], source=[], target=[], context=[], events=[], details=[], protocol=[], activities=[], provider=[], relationships=[]}, topLevelItems={items=ResourceSimplifiedHierarchyItem [path=ROOT_/, code=at0000, itemType=CLUSTER, level=0, text=null, description=null, comment=null, uncommonOntologyItems=null, occurencesFormal=1..1, occurencesText=Obligatorisk, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=null, extendedValues=null]}, addHierarchyItemsTo=items, currentHierarchyItemsForAdding=[ResourceSimplifiedHierarchyItem [path=/items[at0330], code=at0330, itemType=ELEMENT, level=1, text=Neoadjuvant therapy given, description=Has neoadjuvant therapy been given?, comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0331::Yes [Neoadjuvant therapy has been given.] at0332::No [Neoadjuvant therapy has not been given.] at0333::Not known [It is not known if neoadjuvant therapy has been given.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0006], code=at0006, itemType=SLOT, level=1, text=Resection margin, description=Details about a specified resection margin, including the distance from the tumour to the margin., comment=null, uncommonOntologyItems=null, occurencesFormal=0.., occurencesText=Valgfritt, gjentagende, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Inkluder:* openEHR-EHR-CLUSTER.tumour_resection_margins.v0, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004], code=at0004, itemType=CLUSTER, level=1, text=Macroscopic findings, description=Macroscopic anatomical pathology findings related to colorectal cancer., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0005], code=at0005, itemType=SLOT, level=2, text=Tumour dimensions, description=Details of maximum dimensions of the tumour., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Inkluder: openEHR-EHR-CLUSTER.physical_properties.v0 og spesialiseringer, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0007], code=at0007, itemType=ELEMENT, level=2, text=Maximum extramuscular extension, description=The maximum extramuscular extension of the tumour., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=C_DV_QUANTITY, bindings=null, values=Egenskap: Length Enheter: >=0.0 mm, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0008], code=at0008, itemType=ELEMENT, level=2, text=Anastomotic doughnuts submitted, description=Have anastomotic doughnuts been submitted for analysis?, comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_BOOLEAN, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0009], code=at0009, itemType=CLUSTER, level=2, text=Tumour perforation, description=Findings related to tumour perforation., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0009]/items[at0010], code=at0010, itemType=ELEMENT, level=3, text=Tumour perforation, description=Finding of tumour perforation. Tumor perforation is a macroscopically visible defect through the tumor, so that the bowel lumen is in communication with the external surface of the resection specimen., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0018::Present [Tumour perforation is present.] at0019::Absent [Tumour perforation is absent.] at0420::Equivocal [It is uncertain whether a tumour perforation is present.] at0017::Indeterminate [Presence of tumour perforation has not been determined.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0009]/items[at0011], code=at0011, itemType=ELEMENT, level=3, text=Perforation location, description=The location of a perforation, if present., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0020::Retro/infra peritoneal [The perforation is retro/infra peritoneal.] at0021::Serosal [The perforation is serosal.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0009]/items[at0012], code=at0012, itemType=ELEMENT, level=3, text=Comment, description=Narrative comment on the perforation., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0013], code=at0013, itemType=CLUSTER, level=2, text=For rectal tumours, description=Findings related solely to rectal tumours., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0013]/items[at0014], code=at0014, itemType=ELEMENT, level=3, text=Relationship to anterior peritoneal reflection, description=The relationship of rectal tumour to the lowest level of the anterior peritoneal reflection., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0022::Entirely above [The tumour is entirely above the level of the peritoneal reflection anteriorly.] at0023::Astride [The tumour is astride (or at) the level of the peritoneal reflection anteriorly.] at0024::Entirely below [The tumour is entirely below the level of the peritoneal reflection anteriorly.] at0372::Indeterminate [Relationship to anterior peritoneal reflection has not been determined.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0013]/items[at0015], code=at0015, itemType=ELEMENT, level=3, text=Intactness of the mesorectum, description=An assessment of the intactness of the mesorectum. The specimen is scored according to the worst area., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0027::Complete [A good bulk of mesorectum with a smooth surface. No coning near the tumor. No defects more than 5 mm deep.] at0026::Nearly complete [Moderate bulk of mesorectum. Irregular surface with defects greater than 5 mm, but not extending to the muscularis propria. Moderate degree of coning may be seen.] at0025::Incomplete [Little bulk of mesorectum, very irregular with defects down to the muscularis propria.] at0028::Indeterminate [Intactness of the mesorectum has not been determined.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0004]/items[at0373], code=at0373, itemType=ELEMENT, level=2, text=Comment, description=A text comment on the macroscopic findings., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001], code=at0001, itemType=CLUSTER, level=1, text=Microscopic findings, description=Microscopic anatomical pathology findings related to colorectal cancer., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0033], code=at0033, itemType=ELEMENT, level=2, text=Histological tumour type, description=Histologic classification of the tumour., comment=Use of a terminology is preferred. Commonly the WHO classification is used., uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Mulige datatyper: Kodet tekst at0034::Adenocarcinoma [Usual type of colorectal carcinoma.] [ICD-O-3.1::81403] [SNOMED-CT::35917007 \| Adenocarcinoma] at0410::Adenocarcinoma, cribriform comedo-type [Carcinoma with extensive large cribriform glands with central necrosis.] [ICD-O-3.1::82013] [SNOMED-CT::733838009 \| Cribriform comedo-type adenocarcinoma] at0039::Medullary carcinoma [Variant with a solid architecture and prominent tumor infiltrating lymphocytes.] [ICD-O-3.1::85103] [SNOMED-CT::32913002 \| Medullary carcinoma] at0411::Adenocarcinoma, micropapillary type [Variant with small clusters of tumor cells within stromal spaces.] [ICD-O-3.1::82653] [SNOMED-CT::733878002 \| Micropapillary adenocarcinoma] at0035::Mucinous adenocarcinoma [Variant of adenocarcinoma with more than 50% extracellular mucin.] [ICD-O-3.1::84803] [SNOMED-CT::72495009 \| Mucinous adenocarcinoma] at0412::Adenocarcinoma, serrated type [Variant with glandular serration similar to a sessile serrated polyp.] [ICD-O-3.1::82133] [SNOMED-CT::450948005 \| Serrated adenocarcinoma] at0036::Signet ring cell carcinoma [Variant of adenocarcinoma with more than 50% signet ring cells.] [ICD-O-3.1::84903] [SNOMED-CT::87737001 \| Signet ring cell carcinoma] at0038::Adenosquamous carcinoma [A neoplasm comprising both adenocarcinoma and squamous cell carcinoma.] [ICD-O-3.1::85603] [SNOMED-CT::59367005 \| Adenosquamous carcinoma] at0413::Spindle cell carcinoma [A biphasic carcinoma with a spindle- cell sarcomatoid component in which the tumour cells are at least focally immunoreactive for keratins.] [ICD-O-3.1::80323] [SNOMED-CT::65692009 \| Spindle cell carcinoma] at0037::Squamous cell carcinoma [Primary squamous carcinoma excluding upwardly spreading anal tumours.] [ICD-O-3.1::80703] [SNOMED-CT::28899001 \| Squamous cell carcinoma] at0041::Undifferentiated carcinoma [Carcinoma without gland formation, mucin, squamous or neuroendocrine differentiation.] [ICD-O-3.1::80203] [SNOMED-CT::38549000 \| Carcinoma, undifferentiated] at0040::Neuroendocrine tumour G1 [A tumour with neuroendocrine features and a mitotic sount <2 per 10 HPF and/or < 3% Ki67 index.] [ICD-O-3.1::82403] [SNOMED-CT::127572005 \| Neuroendocrine tumour grade 1] at0414::Neuroendocrine tumour G2 [A tumour with neuroendocrine features and a mitotic sount 2-20 per 10 HPF and/or 3-20% Ki67 index.] [ICD-O-3.1::82493] [SNOMED-CT::127573000 \| Neuroendocrine tumour grade 2] at0418::Neuroendocrine carcinoma [A carcinoma with neurendocrine features and a mitotic count >20 per 10 HPF and/or >20% Ki67 index.] [ICD-O-3.1::82463] [SNOMED-CT::55937004 \| Neuroendocrine tumour] at0415::Neuroendocrine carcinoma, large cell [A carcinoma with neurendocrine features composed of intermediate to large cells with a mitotic count >20 per 10 HPF and/or >20% Ki67 index.] [ICD-O-3.1::80133] [SNOMED-CT::128628002 \| Large cell neuroendocrine carcinoma] at0416::Neuroendocrine carcinoma, small cell [A carcinoma with neurendocrine features composed of small cells with a mitotic count >20 per 10 HPF and/or >20% Ki67 index.] [ICD-O-3.1::80413] [SNOMED-CT::719105002 \| Small cell neuroendocrine carcinoma] at0417::Mixed adenoneuroendocrine carcinoma [A carcinoma with morphologicalle recognizable phenotype composed of both epithelial and neuroendocrine elements where at least 30% of either component is identified.] [ICD-O-3.1::82443] [SNOMED-CT::51465000 \| Mixed adenoneuroendocrine carcinoma] Fri eller kodet tekst , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0002], code=at0002, itemType=SLOT, level=2, text=pTNM classification, description=pTNM pathological classification., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Inkluder: openEHR-EHR-CLUSTER.tnm_stage_pathological.v0, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0323], code=at0323, itemType=ELEMENT, level=2, text=Distance of invasion, description=Maximal distance of tumour invasion beyond the muscularis propria., comment=Only applicable for tumors invading beyond the muscularis propria (T3) and not yet having invaded the peritoneum or adjacent structures., uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=C_DV_QUANTITY, bindings=null, values=Egenskap: Length Enheter: >=0.0 mm, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0389], code=at0389, itemType=CLUSTER, level=2, text=Response to neoadjuvant therapy, description=Assessment of response to neoadjuvant therapy., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0389]/items[at0390], code=at0390, itemType=ELEMENT, level=3, text=Description, description=Text description of regression changes after neoadjuvant therapy., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0389]/items[at0003], code=at0003, itemType=SLOT, level=3, text=Details, description=Details of response to neoadjuvant therapy., comment=For example different grading systems, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Inkluder: Alle ikke eksplisitt ekskluderte arketyper, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0269], code=at0269, itemType=CLUSTER, level=2, text=Histological grading, description=Histological tumour grade., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0269]/items[at0391], code=at0391, itemType=SLOT, level=3, text=Grade, description=Histological grading system for colorectal carcinoma., comment=Only adenocarcinomas (not otherwise specified) are graded with a grading system. Squamous cell carcinomas are graded with 3 grades. Tumours after neoadjuvant therapy are not graded. , uncommonOntologyItems=null, occurencesFormal=0.., occurencesText=Valgfritt, gjentagende, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=Not_Set, bindings=null, values=Inkluder:* Alle ikke eksplisitt ekskluderte arketyper, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0269]/items[at0271], code=at0271, itemType=ELEMENT, level=3, text=Comment, description=A text comment on histological grading., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0030], code=at0030, itemType=CLUSTER, level=2, text=Lymph node findings, description=Findings related to the involvement of tumour in lymph nodes., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0030]/items[at0087], code=at0087, itemType=SLOT, level=3, text=Lymph node detail, description=Findings related to the involvement of tumour in lymph nodes., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Inkluder: openEHR-EHR-CLUSTER.lymph_node_metastases.v1, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0030]/items[at0365], code=at0365, itemType=ELEMENT, level=3, text=Status of apical lymph node, description=Status of the highest lymph node closest to the main vascular tie(s)., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0376::Metastasis present [A metastasis in the highest lymph node is detected.] at0377::Metastasis absent [A metastasis in the highest lymph node is not detected.] at0378::Equivocal [It is uncertain whether a metastasis is present or not.] at0379::Indeterminate [The status of the highest lymph node could not be assessed, e.g. because the resection did not contain an apical lymph node.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0030]/items[at0348], code=at0348, itemType=ELEMENT, level=3, text=Comment, description=An additional text comment on lymph node findings., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0403], code=at0403, itemType=CLUSTER, level=2, text=Tumour deposits, description=Details about tumour deposits., comment=Tumour deposits (satellites) are discrete macroscopic or microscopic nodules of cancer in the pericolorectal adipose tissue’s lymph drainage area of a primary carcinoma that are discontinuous from the primary and without histological evidence of residual lymph node or identifiable vascular or neural structures. , uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0403]/items[at0404], code=at0404, itemType=ELEMENT, level=3, text=Assessment of tumour deposits, description=Simple assessment of tumour deposits., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0405::Present [Tumour deposits are detected.] at0406::Absent [Tumour deposits are not detected.] at0407::Equivocal [Det er uncertain whether tumour deposits are present or absent.] at0408::Indeterminate [Presence or absence of tumour deposits has not been assessed.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0403]/items[at0281], code=at0281, itemType=ELEMENT, level=3, text=Number of tumour deposits, description=Number of tumour deposits. Only relevant if lymph node metastasis is absent., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0380::Not applicable [If positive lymph nodes are present, the status of tumour deposits is irrelevant and thus not applicable.] at0388::0 [Tumor deposits are absent.] at0381::1 [One tumor deposit is present.] at0382::2 [Two tumor deposits are present.] at0383::3 [Three tumor deposits are present.] at0384::4 [Four tumor deposits are present.] at0385::5 [Five tumor deposits are present.] at0386::>5 [More than five tumor deposits are present.] at0387::Equivocal [It is uncertain whether tumor deposits are present.] at0284::Indeterminate [Presence of tumour deposits has not been determined.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0403]/items[at0409], code=at0409, itemType=ELEMENT, level=3, text=Comment, description=Comment on tumour deposits., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0278], code=at0278, itemType=CLUSTER, level=2, text=Local tissue invasion, description=Findings related to local tissue invasion by tumour., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0278]/items[at0374], code=at0374, itemType=SLOT, level=3, text=Large vessel (venous) invasion, description=Details of venous tumour invasion., comment=null, uncommonOntologyItems=null, occurencesFormal=0.., occurencesText=Valgfritt, gjentagende, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Inkluder:* openEHR-EHR-CLUSTER.tumour_invasion.v1, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0278]/items[at0277], code=at0277, itemType=SLOT, level=3, text=Small vessel invasion, description=Details of tumour invasion in thin-walled structures (lymphatics, capillaries, venules)., comment=null, uncommonOntologyItems=null, occurencesFormal=0.., occurencesText=Valgfritt, gjentagende, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Inkluder:* openEHR-EHR-CLUSTER.tumour_invasion.v1, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0278]/items[at0286], code=at0286, itemType=SLOT, level=3, text=Perineural invasion, description=Details of perineural invasion by tumour., comment=null, uncommonOntologyItems=null, occurencesFormal=0.., occurencesText=Valgfritt, gjentagende, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Inkluder:* openEHR-EHR-CLUSTER.tumour_invasion.v1, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0263], code=at0263, itemType=CLUSTER, level=2, text=Distant metastasis, description=Findings related to distant metastasis., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0263]/items[at0264], code=at0264, itemType=ELEMENT, level=3, text=Distant metastasis, description=Findings of histologically confirmed distant metastasis., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0362::Present [Evidence of distant metastasis.] at0363::Absent [No evidence of distant metastasis.] at0364::Indeterminate [Evidence of metastasis has not been determined.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0263]/items[at0287], code=at0287, itemType=SLOT, level=3, text=Sites, description=Details of sites of histologically confirmed distant metastases., comment=null, uncommonOntologyItems=null, occurencesFormal=0.., occurencesText=Valgfritt, gjentagende, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Inkluder:* openEHR-EHR-CLUSTER.anatomical_location.v1, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0263]/items[at0265], code=at0265, itemType=ELEMENT, level=3, text=Description, description=A text description of distant metastases., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0366], code=at0366, itemType=CLUSTER, level=2, text=Polyps, description=Findings of polyps., comment=null, uncommonOntologyItems=null, occurencesFormal=0.., occurencesText=Valgfritt, gjentagende, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0366]/items[at0359], code=at0359, itemType=ELEMENT, level=3, text=Type of polyp, description=Type of polyp. Coding of the specific polyp with a terminology is preferred, where possible., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0366]/items[at0338], code=at0338, itemType=ELEMENT, level=3, text=Number of polyps, description=Number of polyps specified above., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_COUNT, bindings=null, values=min: >=0 , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0366]/items[at0367], code=at0367, itemType=ELEMENT, level=3, text=Polyposis syndrome, description=Evidence of polyposis syndrome., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values= at0368::Present [There is evidence of polyposis syndrome.] at0369::Absent [There is no evidence of polyposis syndrome.] at0419::Equivocal [It is uncertain whether a polyposis syndrome is present.] at0370::Indeterminate [Evidence of polyposis syndrome has not been determined.] , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0366]/items[at0371], code=at0371, itemType=ELEMENT, level=3, text=Comment, description=Comment concerning polyps., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0179], code=at0179, itemType=CLUSTER, level=2, text=Additional findings, description=Additional histopathological findings., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=1.., cardinalityText= (Kardinalitet: 1.., usortert), subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0179]/items[at0250], code=at0250, itemType=ELEMENT, level=3, text=Additional finding, description=A single additional histopathological finding., comment=null, uncommonOntologyItems=null, occurencesFormal=0.., occurencesText=Valgfritt, gjentagende, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Mulige datatyper: Kodet tekst at0293::Synchronous carcinoma [Synchronous carcinoma is present.] at0294::Ulcerative colitis [Ulcerative colitis is present.] at0295::Ulcerative colitis with dysplasia [Ulcerative colitis with dysplasia is present.] at0296::Crohn's disease [Crohn's disease is present.] at0297::Crohn's disease with dysplasia [Crohn's disease with dysplasia is present.] at0340::Diverticulosis [Diverticulosis is present.] Fri eller kodet tekst , extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0179]/items[at0220], code=at0220, itemType=ELEMENT, level=3, text=Description, description=A text description of additional findings., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0001]/items[at0309], code=at0309, itemType=ELEMENT, level=2, text=Comment, description=A text comment on the microscopic findings., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Valgfritt, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null]], minIndents={}, termBindingRetrievalErrorMessage=null]